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Bioinert Materials

            Biologically inert, or Bioinert materials are ones which do not initiate a response or interact when introduced to biological tissue. In other words, introducing the material to the body will not cause a reaction with the host. The reason that this type of material has been conceived is because materials initiating a response may detrimentally affect the host [1]. Originally, these materials were used for vascular surgery due to the need for surfaces, which do not cause clotting of the blood. For this reason bioinert materials may sometimes also be called haemocompatible [2]. Even though there is no detrimental affect due to a material being bioinert, it may mean that the tissue does not attach to the material as well as it may to a bioactive material [1].    
            Realistically, most materials are not completely bioinert and no synthetic material is bioinert [2]. Some examples of bioinert, or very close to bioinert substances are Ttianium-Aluminum Vanadium Alloy (used in hip replacements) [1], phosphoryl choline (PC) (used in contact lenses), Polyethylene oxide polymers (PEO) [2] and Diamond.


1. Blokhuis, Taco J., Marco F. Termaat, Frank C. Den Boer, Peter Patka, Fred C. Bakker, and Henk J. Haarman. "Properties of Calcium Phosphate Ceramics in Relation to Their in Vivo Behavior." The Journal of Trauma, Injury, Infection and Critical Care 48 (2000): 179. Ovid. Drexel University, Philadelphia. 25 Aug. 2007.
2.  Bruce, Allan. "Closer to Nature: New Biomaterials and Tissue Engineering In." British Journal of Opthamology 83 (1999): 1235-1240. 20 Aug. 2007 <http://bjo.bmj.com/cgi/reprint/83/11/1235>