Data Fusion Laboratory
 
Anthony Lowman
  Associate Dean of Engineering
Associate Professor of Chemical Engineering
 
Degrees
  BS Chemical Engineering
University of Virginia 1993
PhD Chemical Engineering
Purdue University 1997
 
Research Interests
  - Engineering Hydrogels for Controlled Delivery and Uptake of Protein and Peptides
- Oral Insulin Delivery Using pH-Responsive Complexation Hydrogels
- Chaspmterization of New Hydrogel Copolymers for Nucleus Pulposus Replacement
- Novel Drug Delivery System for Rapid Insulin Uptake
- Design of Mucoadhesive, Nasal Drug Delivery Systems
 
Selected Publications

A.M. Lowman and N.A. Peppas "Oscillatory Drug and Protein Release by a Complexation/Decomplexation Mechanism", Proceed. Intern. Symp. Control. Rel. Bioact. Mater., 23, 745-746 (1996).

A.M. Lowman, T.D. Dziubla, and N.A. Peppas, "Novel Networks and Gels Containing Increased Amounts of Grafted and Crosslinked Poly(Ethylene Glycol)", Polym. Prepr., 38(1), 622-623 (1997).

M. Morishita, K. Takayama, T. Nagai, A.M. Lowman and N.A. Peppas, "Application of a pH-Responsive Polymer to an Insulin Oral Dosage Form," Yakuzaigaku, 57 Suppl., 96-97 (1997), in Japanese.

N.A. Peppas, C.M. Hassan, K.B. Keys, A.M. Lowman, K. Podual and R. Scott, "Biomaterials for Developing Pharmaceutical Preparations of High Quality of Life," Proceed. Conf. Pharm. Techn., 22, 1-6 (1997).

A.M. Lowman and N.A. Peppas, "An Analysis of the Complexation/Decomplexation Phenomena in Graft Copolymer Networks", Macromolecules, 30,4959-4965 (1997).

N.A. Peppas and A.M. Lowman, "Protein Delivery from Novel Bioadhesive Complexation Hydrogels," in S. Frokjaer, L. Christrup and P. Krogsgaard-Larsen, eds., Peptide and Protein Delivery, Alfred Benzon Symposium, 43, Munksgaard, Copenhagen, 206-216 (1998).

A.M. Lowman and N.A. Peppas, "Drug Transport Analysis in Complexed Networks Using Molecular Probes", Proceed. Intern. Symp. Control. Rel. Bioact. Mater., 25, 244-245 (1998).

A.M. Lowman, N.A. Peppas, M. Morishita and T. Nagai, "Novel Bioadhesive Complexation Networks for Oral Protein Delivery," in I. McCullough and S. Shalaby, eds., Tailored Polymeric Materials for Controlled Delivery Systems, ACS Symposium Series, Vol. 709, 156-164, ACS, Washington, DC, 1998.

A.M. Lowman and N.A. Peppas, "Hydrogels", in E. Mathiowitz, ed., Encyclopedia of Controlled Drug Delivery, 397-418, John Wiley and Sons, New York, 1999.

A.M. Lowman and N.A. Peppas, "Pulsatile Drug Delivery Based on a Complexation/Decomplexation Mechanism," in S.M. Dinh, J.D. DeNuzzio and A.R. Comfort, eds., Intelligent Materials for Controlled Release Technologies, ACS Symposium Series, Vol. 728, 30-42, ACS, Washington, DC, 1999

A.M. Lowman, M. Morishita, M. Kajita, T. Nagai and N.A. Peppas, "Oral Delivery of Insulin Using pH-Responsive Complexation Gels," J. Pharm. Sci., 88, 933-937 (1999).

K. Nakamura, Y. Maitani, A.M. Lowman, K. Takayama, N.A. Peppas and T. Nagai. "Uptake and release of budesonide from mucoadhesive, pH-sensitive copolymers and their application to nasal delivery," J. Controlled Release, 61, 329-335 (1999).

N.A. Peppas, K.B. Keys, M. Torres-Lugo and A.M. Lowman, "Poly(ethylene glycol)-containing Hydrogels in Drug Delivery," J. Controlled Release, 62, 81-88 (1999).

A.M. Lowman and N.A. Peppas, "Solute Transport Analysis in pH-Responsive, Complexing Hydrogels of Poly(Methacrylic Acid-g-Ethylene Glycol)," J. Biomat. Sci., Polym. Ed., 10, 999-1009 1999.

A.M. Lowman and N.A. Peppas, "Molecular Analysis of Interpolymer Complexation in Graft Copolymer Networks," Polymer, 41, 73-80 (2000).

A.M. Lowman, "Complexing Polymers in Drug Delivery," in D.L. Wise, ed., Handbook of Pharmaceutical Controlled Release Technology, Marcel Dekker, Inc., in press, 1999.

A.M. Lowman, B.A. Cowans and N.A. Peppas. Solid-state NMR Investigation of Interpolymer Complexation in Swollen Polyelectrolyte Networks. J. Polym. Sci., Polym. Phys. Ed., (submitted).

A.M. Lowman and M. Marcolongo, "Associating Hydrogels of PVA/PVP as Novel Biomaterials," Biomaterials, (submitted).

   
BIOMATERIALS AND DRUG DELIVERY LABORATORY- DIRECTOR: ANTHONY LOWMAN (ALOWMAN AT DREXEL.EDU)