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Publications

Pubmed link to Publications

2009

Yu J.J., Robb V.A., Morrison T.A., Ariazi E.A., Karbowniczek M., Astrinidis A., Wang C., Hernandez-Cuebas L., Seeholzer L.F., Nicolas E., Hensley H., Jordan V.C., Walker C.L. and Henske E.P. (2009) Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells. Proceedings of the National Academy of Sciences USA (published online before print 6 February, 2009)

 

2006

Astrinidis A. and Henske E.P. (2006) Mutation detection in tumor suppressor genes using archival tissue specimens. Methods Molecular Medicine 126: 185-196 (Congenital Heart Disease: Molecular Diagnistics, M. Kearns-Jonker ed.)

Robb V.A., Astrinidis A., Henske E.P. (2006) Frequent hyperphosphorylation of ribosomal protein S6 in lymphangioleiomyomatosis-associated angiomyolipomas. Modern Pathology 19: 839-846

Astrinidis A., Senapedis W., Henske E.P. (2006) Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent mannter. Human Molecular Genetics 15: 287-297 [Epub 2005 Dec 8]

 

2005

Astrinidis A. and Henske E.P. (2005) Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease. Oncogene 14: 7475-81. Review.

 

2004

Astrinidis A. and Henske E.P. (2004) Aberrant cellular differentiation and migration in renal and pulmonary tuberous sclerosis complex. Journal of Child Neurology 19: 710-5. Review.

Karbowniczek M., Cash T., Cheung M., Robertson G.P., Astrinidis A., Henske E.P. (2004) Regulation of B-Raf kinase activity by tuberin and Rheb is mTOR independent. Journal of Biological Chemistry 279: 29930-29937 [Epub 2004 May 18]

 

2003

Astrinidis A., Senapedis W., Coleman T.R., Henske E.P. (2003) Cell cycle-regulated phosphorylation of hamartin, the product of the tuberous sclerosis complex 1 gene, by CDK1/cyclin B. Journal of Biological Chemistry 278: 51372-51379 [Epub 2003 Oct 09]

Yu J.J., Astrinidis A., Howard S., Henske E.P. (2004) Estradiol and tamoxifen stimulate lymphangiomyomatosis-associated angiomyolipoma cell growth and activate both genomic and non-genomic signaling pathways. American Journal of Physiology - Lung Cell Molecular Physiology 286: L694-700 [Epub 2003 Aug 15]

 

2002

Astrinidis A., Cash T., Hunter D., Walker C., Chernoff J., Henske E.P. (2002) Tuberin, the Tuberous Sclerosis 2 tumor suppressor gene product, regulates Rho activation, cell adhesion, and cell migration. Oncogene 21: 8470-8476

Karbowniczek M., Astrinidis A., Balsara B.R., Testa J.R., Lium J.H., Colby T.V., McCormack F.X., Henske E.P. (2002) Recurrent lymphangiomyomatosis after transplantation: genetic analyses reveal a metastatic mechanism. American Journal of Respiratory and Critical Care Medicine 167: 976-982

Khare L., Astrinidis A., Senapedis W., Adams P.D., Henske E.P. (2002) Expression of wild type and mutant TSC2, but not TSC1, causes an increase in the G1 fraction of the cell cycle in HEK293 cells. Journal of Medical Genetics 39: 676-80

 

2001

Yu J.J., Astrinidis A., Henske E.P. (2001) Chromosome 16 loss of heterozygosity in tuberous sclerosis and sporadic lymphangiomyomatosis. American Journal of Respiratory and Critical Care Medicine 164: 1537-40

 

2000

Carsillo T., Astrinidis A., Henske E.P. (2000) Mutations in the tuberous sclerosis complex gene TSC2 are a cause of sporadic pulmonary lymphangioleiomyomatosis. Proceedings of the National Academy of Sciences USA 97: 6085-6090

Astrinidis A., Khare L., Carsillo T., Smolarek T., Au K.S., Northrup H., Henske E.P. (2000) Mutational analysis of the tuberous sclerosis gene TSC2 in patients with pulmonary lymphangioleiomyomatosis. Journal of Medical Genetics 37: 55-57

 

1999

Valianou M.G., Kouvatsi A., Hassapopoulou-Matamis H., Astrinidis A., Triantaphyllidis C. (1999) Heterogeneity of four beta-thalassaemia mutations in Greece. Hemoglobin 23: 79-82

Ivanova R., Astrinidis A., Lepage V., Djoulah S., Wijnen E., Vu-Trieu A.N., Hors J., Charron D. (1999) Mitochondrial DNA polymorphism in the Vietnamese population. European Journal of Immunogenetics 26: 417-422

Ivanova R., Astrinidis A., Djoulah S., Lepage V., Wijnen E., Hors J., Charron D. (1999) Mitochondrial DNA polymorphisms of a west Algerian population (Oran region). Biomedical Pharmacotherapy 53: 386-392

Ivanova R., Astrinidis A., Lepage V., Kouvatsi A., Djoulah S., Hors J., Charron D. (1999) Mitochondrial DNA polymorphism in the French population. Biomedical Pharmacotherapy 53: 207-212

Ivanova R., Astrinidis A., Lepage V., Wijnen E., Naumova E., Charron D. (1999) Mitochondrial DNA polymorphism in the Bulgarian population. Balkan Journal of Medical Genetics 2: 9-16

 

1998

Astrinidis A., Kouvatsi A., Nahmias J., Povey S., Pandeliadis C., Danzaki A.,Schneider M., Triantaphyllidis C. (1998) Novel intragenic polymorphisms in the tuberous sclerosis 2 (TSC2) gene. Human Mutation 12: 217 (abstract) / on line mutation in brief #184

Astrinidis A. (1998) Molecular Study of Tuberous Sclerosis. PhD Thesis, Aristotle University of Thessaloniki, Thessaloniki, Greece

 

1994

Astrinidis A., Kouvatsi A. (1994) Mitochondrial DNA polymorphisms in Northern Greece. Human Biology 66: 601-611

 
 

©2007-2009 Aristotelis Astrinidis