MEM 444 Biofluid Mechanics Winter (Jan. - March, 2008) (updated 1-23-08)
Class Time and Location: Tuesday 6 – 9 PM, Room 3-326
Professor: Young I. Cho
Department of Mechanical Engineering and Mechanics, Drexel University
Tel: 215-895-2425; Email: choyi@ drexel.edu; Office: 3-157 (Main Building)
Office hour: Tuesday 4-6 PM
TA: Mr. Doh-Hyoung Lee, Hess lab, Room 113H, office phone: 215-895-2174.
Class Schedule
Week 1: Chapter 1 Introduction
Chapter 2 Reviews of Basic Fluid Mechanics (HW problems: solutions part 1, part 2) (Summary of Fluid equations)
Week 2: Chapter 3 Circulatory System: Names of arteries: Names of valves in the heart
Chapter 4 Pressure and Flow profiles, Arteriosclerosis, Pulse Wave Velocity (HW problems: solutions)
Week 3: Chapter 5 Heart and Heart Physiology
Chapter 6 Structure of arterial vessels, Peripheral vessels, Veins
Chapter 7 Auto-regulation of blood flow
Week 4: Chapter 8 Vascular Diseases and Atherosclerosis
Chapter 9 Interventions, Angioplasty (Balloon, Stent, Bypass), Angiography
Week 5: Chapter 10 Bifurcation Flows
Chapter 11 Flow Analysis, Windkessel Model
Week 6: Chapter 12 Straight tube (steady and unsteady flows)
Chapter 13 In Vitro Biofluid Experiments, CFD simulation of blood flows
Week 7: Chapter 14 Precursor of Atherosclerosis, - Cholesterol and obesity
Chapter 15 Measurements of Properties of Blood
Week 8: Chapter 16 Hemorheology, Viscometers, Yield Stress
Chapter 17 Electrocardiograms
Week 9: Chapter 18 Transport of Ions, Across Cell Membrane
Chapter 19 Transport of water, Osmosis and osmotic pressure
Chapter 20 Water (Dehydration)
Week 10: Chapter 21 Oxygen and Hemoglobin (Hgb)
Chapter 22 Hemodilution
Chapter 23 Hemodialysis
Chapter 24 Aneurysm, Hydrocephalus Shunt
Overview of the course
This course introduces basic anatomy and pathophysiology related to blood flows in the circulation system. Mathematical modeling of a pulsatile blood flow will be introduced. Biomedical devices for the measurements of blood pressure and flow will be introduced. In addition, measurement techniques of blood properties will be introduced.