Selected Publications

Khan M.Z., Brandimarti R., Shimizu S., Nicolai J., Crowe E., and Meucci O, The chemokine CXCL12 promotes survival of post-mitotic neurons by regulating Rb protein. Cell Death & Differentiation (in press). [PDF file]

Burbassi, S. Aloyo V, Chaijale N., Simansky K., and Meucci O. GTPgS incorporation in the rat brain: a study on m-opioid receptors and CXCR4, Journal of NeuroImmune Pharmacology (2008) 3:26-34. [PDF file]

Jamieson W., Shimizu S., D’Ambrosio J., Meucci O., and Fatatis A., CX3CR1 is expressed by prostate epithelial cells and androgens regulate the levels of CX3CL1/Fractalkine in the bone marrow: potential role in prostate cancer bone tropism, Cancer Research (2008) 68(6):1715-22. [PDF file]

Shimizu S, Khan MZ, Hippensteel R.L., Parkar A, Raghupathi, and Meucci O. “Role of the transcription factor E2F1 in CXCR4-mediated neurotoxicity and HIV neuropathology”, Neurobiology of Disease 25: 17-26, (2007). [PDF file]

Bardi G, Sengupta G, Khan MZ, Patel JP and Meucci O., “HIV gp120-induced apoptosis of human neuroblastoma cells in the absence of CXCR4 internalization”, Journal of NeuroVirology 2: 211-218, 2006. [PDF file]

Patel JP, Sengupta R, Bardi G, Khan MZ, Mullen-Przeworski A., and Meucci O. “Modulation of neuronal CXCR4 by the µ-opioid specific agonist DAMGO” Journal of NeuroVirology 12:1-9, (2006). [PDF file] (Note: This PDF file is 17MB)

Khan M.Z, Shimizu S., Patel J., Nelson A., Le M-T., Mullen-Przeworski A., Brandimarti R., Fatatis A., and Meussi O. “Regulation of neuronal p53 activity by CXCR4”, Mol. Cell. Neurosci. 30(1):58-66, (2005). [PDF file]

Dolloff N.G, Shulby S.S., Nelson A.V, Stearns M.E., Johannes G.J, Thomas J.D., Meucci O., and Fatatis A. “Bone-metastatic potential of human prostate cancer cells correlates with Akt/PKB activation by alpha Platelet Derived Growth Factor Receptor”, Oncogene, 24:6848-6854 (2005). [PDF file]

Khan M.Z., Brandimarti R., Patel J.P., Huynh N., Wang J., Huang Z., Fatatis A., and Meucci O. Apoptotic and anti-apoptotic effects of CXCR4: is it a matter of intrinsic efficacy? Implications for HIV neuropathogenesis. AIDS Research and Human Retroviruses 20:1063-71 (2004). [PDF file]

Shulby S.A, Dolloff N.G, Stearns M.E., Meucci O., and Fatatis A CX3CR1-fractalkine expression regulates cellular mechanisms involved in adhesion, migration and survival of human prostate cancer cells. Cancer Research, 64:4693-4698 (2004). [PDF file]

Brandimarti R., Khan M.Z., Fatatis A. and Meucci O. Regulation of cell cycle proteins by chemokine receptors: a novel pathway in HIV neuropathogenesis? Journal of NeuroVirology 10: 1-5 (2004). [PDF file]

Khan M.Z., Brandimarti R., Musser B.J., Resue D.M., Fatatis A., and Meucci O. The chemokine receptor CXCR4 regulates cell cycle proteins in neurons. Journal of NeuroVirology 9:300-314 (2003). [PDF file]

Roncarati R, Sestan N, Scheinfeld MH, Berechid BE, Lopez PA, Meucci O, McGlade JC, Rakic P, D'Adamio L. The γ-secretase-generated intracellular domain of β-amyloid precursor protein binds Numb and inhibits Notch signaling. PNAS 99:7102-7 (2002). [PDF file]

Meucci O., Fatatis A., Simen A.A., and Miller R.J. Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival. PNAS 97: 8075-8080 (2000). [PDF file]

Miller R.J. and Meucci O. AIDS and the brain: is there a chemokine connection? Trends in Neuroscience 22:471-470, (1999). [PDF file]

Meucci O., Fatatis A., Simen A.A., Bushell T.J. Gray P.W. and Miller R.J. Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity. PNAS 95: 14500-505, (1998). [PDF file]

Meucci O. and Miller R.J. Dissociation between Joro spider toxin sensitivity of recombinant AMPA receptors and their ability to increase intracellular calcium Neuropharmacology 37:1431-1443 (1998).

Meucci O. and Miller R.J. gp120-induced neurotoxicity in hippocampal pyramidal neuron cultures: protective action of TGF-b1. J. Neurosci. 16:4080-4088 (1996).

Meucci O., Fatatis A., Holzwarth J. and Miller R.J., Developmental regulation of the toxin sensitivity of Ca2+ permeable AMPA receptors in cortical glia. J.Neurosci. 16:519-530 (1996). [PDF file]