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The balance of signals promoting cell survival and
apoptosis is critical for the maintenance and renewal of differentiated
tissues, and its disruption is associated with such devastating
pathologies as cancer and neurodegenerative diseases, including
neuroAIDS.
Research in this laboratory is focused on the cellular
and molecular mechanisms that regulate neuronal survival/differentiation,
and the events underlying the neuro-pathogenesis of AIDS. Thus,
a major area of interest revolves around the roles of chemokine
receptors in the CNS.
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